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CRI-MAP is a programme for the construction of genetic maps from gene linkage data. From the CRI-MAP Manual introduction by its author, Dr. Phil Green ...
"The main purpose of CRI-MAP is to allow rapid, largely automated construction of multilocus linkage maps (and to facilitate the attendant tasks of assessing support relative to alternative locus orders, generating LOD tables, and detecting data errors). Although originally designed to handle codominant loci (e.g. RFLPs) scored on pedigrees "without missing individuals", such as CEPH or nuclear families, it can now (with some caveats described below) be used on general pedigrees, and some disease loci."
In addition to its primary mapping function, CRI-MAP can also estimate recombination fractions & LOD scores between pairs of loci, perform multipoint likelihood calculations, and point out recombinant chromosomes in pedigrees.
This tutorial is divided into three parts:
Throughout, you will find links to:
For those of you without data, please get some from the
For the majority of the exercises, you need to run an interactive login session on the Terminal.
Move this window to the right of your screen, so it "fits" between the up and down scroll bar arrows of your web browser, like this.
Have some fun doing this tutorial, and PLEASE send your
comments and questions!
If you are keen to have MORE information about CRI-MAP,