CRI-MAP - Introduction

---

CRI-MAP tutorial contents:

Manuals: Web & text versions	Web Manual Table of Contents	Tutorial   Practice   Datasets	Formating data with "prepare"	Mapping with "build"	Testing & Extending Maps	Bibliography & Other Links

CRI-MAP is a programme for the construction of genetic maps from gene linkage data. From the CRI-MAP Manual introduction by its author, Dr. Phil Green ...

"The main purpose of CRI-MAP is to allow rapid, largely automated
construction of multilocus linkage maps (and to facilitate the attendant
tasks of assessing support relative to alternative locus orders,
generating LOD tables, and detecting data errors). Although originally
designed to handle codominant loci (e.g. RFLPs) scored on pedigrees
"without missing individuals", such as CEPH or nuclear families, it can
now (with some caveats described below) be used on general pedigrees,
and some disease loci."

In addition to its primary mapping function, CRI-MAP can also estimate recombination fractions & LOD scores between pairs of loci, perform multipoint likelihood calculations, and point out recombinant chromosomes in pedigrees.

This tutorial is divided into three parts:

1. data input & formatting
2. mapping & LOD scores
3. map testing & X-overs

Throughout, you will find links to:

• the CRI-MAP manual (World Wide Web version),
• its Table of Contents,
• and other references.

For those of you without data, please get some from the

• example datasets page.

NB:

This is an INTERACTIVE tutorial; you will benefit most by FOLLOWING the instructions, through READING the examples, and DOING the exercises! Exercises are indicated by italics in nested paragraphs ...

Exercise X.y: ... like this!

For the majority of the exercises, you need to run an interactive login session on the Terminal.
Move this window to the right of your screen, so it "fits" between the up and down scroll bar arrows of your web browser, like this.

Now you are ready for
Part 1 - data input & formatting  

Have some fun doing this tutorial, and PLEASE send your comments and questions!

If you are keen to have MORE information about CRI-MAP, check the Bibliography Page.